Symposium E1
Clinical Implementation of Precision Medicine: From genomewide discovery to practice

Monday 22 May 2017
Stockholmsmässan : A3


With recent initiatives in the U.S. and indeed globally, precision medicine represents a new discipline specifically focused on the translation of genomic discoveries to patient care. However for precision medicine to become a reality major challenges must be addressed. First and foremost, large cohorts of patients with available biological samples and electronic health information are needed to make robust discoveries that can be effectively translated to patient care. Importantly, expert advice on the use of genomic information to guide drug selection and dosing in the context of individual patients from diverse ethnic and racial backgrounds is needed.

This symposium will focus on key issues for implementation of precision medicine in patient practice. Large clinical consortia with electronic health information will be described. Issues relevant to translation of new discoveries will be highlighted, particularly, the use of genetic information to guide the selection of safe and effective therapies.

Co-chair(s): Kathy Giacomini (USA) and Jesse Swen (the Netherlands)


15:00 – 15:10 Genomewide approaches to the clinical implementation of precision treatments in clinical practice – Opening remarks
Kathy Giacomini, University of California, USA

15:10 – 15:45 Pharmacogenetics in Europe: The European Pharmacogenetics Implementation Consortium Initiative
Ron HN van Schaik,Erasmus MC, the Netherlands

15:45 – 16:20 The Japan BioBank and the PGRN-RIKEN Collaboration: Facilitating New Discoveries in Precision Medicine
Michaki Kubo, Center for Integrative Medical Sciences, RIKEN, Japan

16:20 – 16:40 BREAK

16:40 – 17:15 The Clinical Pharmacogenetics Implementation Consortium: Leading translation of precision medicine
Mary Relling, St. Jude's Children's Research Hospital, USA

17:15 – 17:50 Genomewide Approaches to Discovering Drug Safety Biomarkers
Munir Pirmohamed, University of Liverpool, UK

17:50 – 18:00 Concluding remarks
Jesse Swen, Leiden University Medical Center, the Netherlands